In order to improve the quality and progress of the project, the clinical operation adopts the project team responsibility system, with the Beijing project team leading the project management, and the resident project teams assisting the Beijing project team in the central management of the region; Leadingpharm has stationed clinical trial technicians in all provinces except Tibet and Qinghai, and established clinical offices in Shanghai, Guangzhou, Shijiazhuang, Wuhan, Changsha, Hangzhou, Taiyuan, Zhengzhou, Shenyang, Xi'an, Tianjin and other major cities in China.